Fentanyl Addiction, Side Effects, & Rehab Options

Fentanyl has fast become a huge national concern, making headlines in recent years for its increased role in the nation’s overdose epidemic.1,2 If you’re struggling with fentanyl abuse or addiction, we can help. Call us for immediate, confidential assistance at .
Did you know most health insurance plans cover addiction treatment?
About Fentanyl

What Is Fentanyl?

Fentanyl is an extremely strong synthetic (made in a lab) opioid. Fentanyl, which was created as a prescription medication, is also made and sold illegally.3 Illicitly manufactured fentanyl, or IMF, is increasingly being used as cheap filler or added to other illicit drugs and counterfeit pills and has played a major role in the country’s opioid overdose epidemic.2

What Is Prescription Fentanyl Used For?

Prescription fentanyl solution

Prescription fentanyl is mainly utilized for the management of severe pain, such as pain associated with surgical procedures, or for chronic pain in patients who have become tolerant to alternative opioid painkillers.5

Fentanyl is sold and prescribed in several forms (e.g., lozenges, patches or injections) and under many brand names such as:6

  • Duragesic.
  • Sublimaze.
  • Subsys.
  • Actiq.
  • Fentora.

Fentanyl Misuse

As a very powerful prescription opioid, fentanyl does have a high potential for misuse, which can mean:7

  • Taking fentanyl in a way or dose other than prescribed.
  • Taking someone else’s fentanyl.
  • Taking fentanyl with the primary intention of getting high.

Prescription fentanyl may be diverted for illicit use by those seeking it for its euphoric effects, but the major growing problem in the U.S. is fentanyl and fentanyl analogues (chemicals that are structurally similar to fentanyl and have similar effects) that are manufactured illegally and then added to other street drugs such as heroin, meth, cocaine, or MDMA to increase their potency. Illicitly manufactured fentanyl is also increasingly being found in counterfeit pills sold on the streets, such as counterfeit Xanax, OxyContin, and Adderall. Drug users with little to no tolerance for fentanyl who unknowingly use fentanyl-laced substances can easily overdose and die.5

Beginning in 2013, the U.S. began to see a steep rise in overdose deaths involving both prescription and illicitly manufactured fentanyl, a trend which unfortunately is not letting up. Drug overdoses in the U.S. rose by 30% between 2019 and 2020, with officials reporting that fentanyl played a significant role in the increase.1 Of the nearly 70,000 opioid overdoses in 2020, approximately 57,000 involved synthetic opioids such as fentanyl.1


Health Effects

Risks of Fentanyl Use

Fentanyl has some significant health risks, whether taken a prescription or used illegally. Appropriate prescription use monitored by a medical professional will mitigate many of the inherent dangers of fentanyl; however, any misuse of either prescription or illicit fentanyl introduces numerous health risks, including opioid dependency, addiction, and overdose.5  

Immediate Health Effects of Fentanyl Use

Man sitting after using drugs

Like other opioids, fentanyl binds to the body’s opioid receptors to produce pain relief, relaxation, and euphoria.5 The less-desirable side effects of fentanyl are also similar to other prescription and illicit opioids and include:3, 5

  • Drowsiness.
  • Sedation.
  • Confusion.
  • Small pupils.
  • Dizziness.
  • Nausea/vomiting.
  • Difficulty urinating.
  • Constipation.
  • Slowed or difficult breathing.

Fentanyl Overdose

An overdose occurs when a person takes more of a drug than their body can tolerate. Unfortunately, it can take very little fentanyl to cause an overdose. Fentanyl-laced drugs may contain far more fentanyl than would be deadly for the average person. For example, just 2mg of fentanyl can cause a fatal overdose in many people, and the DEA has found more than twice this amount in counterfeit prescription opioid pills.8

Fentanyl can have a synergistic effect with other opioids including heroin, which means a person who takes prescription opioids or who is addicted to heroin has an increased risk of overdose when combining with fentanyl (knowingly or unknowingly).9

The 3 most common symptoms of an opioid overdose, known as the opioid overdose triad, are:10

  • Very tiny (“pinpoint”) pupils.
  • Loss of consciousness.
  • Problems breathing (slowed, stopped or erratic breathing).

Someone exhibiting these or other signs of fentanyl overdose needs immediate medical attention.11 If you suspect someone has overdosed, call 911 immediately and wait with the person until responders arrive.11 If you have naloxone (Narcan or Kloxxado) available, administer a dose.11 Because fentanyl is so potent, additional doses of naloxone may be needed.12 If the person does not resume breathing in 3-5 minutes, administer a second dose.13

Place the person in the recovery position with their top leg and arm crossed over their body to prevent choking should they vomit.11 Do not leave the person alone, even if you’ve been using drugs too. Many states, including Nevada, have Good Samaritan laws that protect you from arrest for drug use if you’re helping someone in an overdose emergency.14

NOTE: It’s extremely important that if you witness an overdose, you call 911, even if administer naloxone. While naloxone will reverse overdose effects for 30-90 minutes, fentanyl will stay in the body for longer and the person may re-experience the effects of overdose if they don’t get medical help.12 

Long-Term Effects of Fentanyl Abuse

Long-term use of opioids including fentanyl can lead to numerous health problems that include:15

  • Chronic constipation and related bowel problems.
  • Mood disorders.
  • Hormonal imbalances in both men and women.
  • Increased fracture risk in older individuals.
  • Suppressed immune system.
  • View more.

One of the most serious risks of fentanyl use is the risk of opioid addiction, a chronic and progressive disease with devastating consequences.5,15 A person who struggles with an addiction to opioids will prioritize the seeking out and using of fentanyl and other opioids, even when doing so harms their health, their relationships, their finances, or other key areas of their life.5

Someone who uses fentanyl long-term may also be dependent on the drug. Dependence is a physiological adaption that is common in those who are addicted but that can occur independent of addiction, as well.16  Dependence to fentanyl can make quitting extremely difficult, as very uncomfortable withdrawal symptoms will arise upon any attempt to significantly cut back on use. Fentanyl withdrawal symptoms include:5

  • Bone and muscle pain.
  • Shivering and goosebumps.
  • Restless legs.
  • Insomnia and/or poor sleep.
  • Diarrhea.
  • Nausea and vomiting.
  • Strong opioid cravings.
Signs of Abuse

What Are the Signs of Fentanyl Abuse?

Someone prescribed fentanyl or other opioids may begin to misuse them. Signs of prescription opioid misuse include:17

  • Falsely reporting a lost or stolen prescription.
  • Asking doctors for early refills of medication.
  • Seeking out fentanyl or other opioids from sources outside of a doctor’s office.
  • Withdrawal symptoms at doctor’s appointments due to prescriptions running out early.
  • Regularly asking for increased amounts of fentanyl or other opioids from one’s doctor.
  • Complaining of increasing pain despite the pain-causing condition not getting worse.
  • Reluctance to consider any non-opioid treatments for pain.
  • Often appearing over-sedated or abnormally sleepy.

Fentanyl Addiction Signs

Someone who has lost control of their fentanyl use may exhibit the signs of an opioid use disorder, which include:18

  • Using opioids in higher amounts or for longer than intended.
  • Trying and failing to quit or cut back on opioids.
  • Spending a large percentage of one’s time in obtaining, using, or recovering from opioids.
  • Failing to attend to one’s personal obligations at home, school or work due to opioid use.
  • Cravings for opioids.
  • Giving up important activities and hobbies in favor of opioid use.
  • Using opioids when doing so can be physically dangerous, such as before using heavy machines or prior to getting behind the wheel.
  • Continuing to use opioids even when it is clearly causing or worsening
    • Social/relationship problems.
    • Physical or psychological heath issues.
  • Needing more opioids to feel their effects.
  • Having to take opioids to avoid withdrawal or feeling withdrawal symptoms upon cutting back.

All of these are representative of a compulsion to use opioids despite the resulting harm. Without treatment, consequences of this compulsive may continue to grow in severity. Fortunately, treatment for opioid use disorder is effective, and it has helped many people recover from addiction.18

Addiction Treatment

Fentanyl Addiction Treatment

The idea of treatment can be daunting when you’re starting to think about recovery from opioid addiction. But it doesn’t have to be. Here’s what you need to know.

First, the process for opioid addiction treatment often begins with medical detox. This is because withdrawal symptoms from opioids such as fentanyl can be very intense and uncomfortable. In some cases, symptoms such as severe electrolyte imbalances or dehydration may need the immediate attention of doctors and nurses.19

In medical detox, you can receive medications to alleviate your withdrawal symptoms and help prevent any medical complications.19 Medical detox can be performed in both inpatient and outpatient environments. At Desert Hope, we offer inpatient medical detox and around-the-clock medical support.

After detox, treatment should continue with a shift in focus from your physical dependence on opioids to the psychological issues that underlie your addiction. Therapy in both individual and group settings can help you uncover and learn new coping skills to deal with past traumas, negative feelings like guilt and shame, ambivalence about recovery, and any other issues that keep you using fentanyl.20,21

Medications may also be a part of your treatment.22 When combined with therapy, medications such as methadone or buprenorphine, can bolster your recovery. Both drugs are effective in retaining people in treatment longer, reducing the risk of opioid overdose, and helping to enable patients to live self-directed lives no longer controlled by opioids.22

Treatment after detox may be inpatient or outpatient, depending on your needs and how much support you have for your recovery at home. Your doctor or treatment team can help you determine which type of program is right for you.

Inpatient programs in Vegas offer a live-in recovery environment with a great deal of support and structure. The lifestyle of active addiction is often a chaotic one, and the structure of this type of program can be hugely beneficial in removing the chaos and creating a supportive environment conducive to introducing healthy habits needed for long-term sobriety.

Outpatient programs come in several forms. Partial hospitalization programs most closely match the treatment services of inpatient programs, as they require attendance at the program many days per week for many hours of the day. Intensive outpatient programs are slightly less intensive, and standard outpatient programs represent the lowest level of intensity.

At Desert Hope, we offer every treatment option from medical detox to inpatient rehab to outpatient treatment. We can talk you through your recovery options when you call us at . We can also help you instantly check your insurance benefits with our quick online benefits check.